Advances in Nutrition United Statesp.
European Journal of Clinical Investigation, p. Immunology Letters, p.
Aurelian Udristioiu¹, Radu G. History: a 70 year old engineer, following 8 years vegetable — dietary, was admitted to the county hospital, in neurology department, with diagnostic of poli-radiculonevrites, received in ward the treatment with milgama containing micro-gram multivitamin. After a lipotimia status the patient was transferred to cardiology department.
Svetlana Matjus Graves' hyperthyroidism has a number of well-recognized but relatively rare extrathyroid manifestations such as thyroid acropachy, pretibial myxedema, and congestive heart failure. A year-old Caucasian woman presented to the out-patient clinic with symptoms of hyperthyroidism lasting for approximately five months.
Macrocytes and ovalocytes where also presented. Biopsy results from gastric mucosa showed lesions of chronic gastritis, non-atrophic epithelium.
Conclusions: Megaloblastosis appears in some time with vitamin B12 deficiently in bone morrow but no in peripheral blood because of administration of multivitamin drugs, deleting haematological shape of megaloblastic anemia. Keywords: Wait blood cells, Erythrocyte sedimentation ratio, haptocorin, transcobalamin. The Corresponding author of this manuscript is Aurelian Neuroendocrine cancer day 2019 of Hematology, Emergency County Hospital Târgu Jiu, Clinical Laboratory, Gorj, and contribution of the authors as mentioned below with their responsibility in the research.
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Ни при каких обстоятельствах, - добавил Синий Доктор, - вы не должны нарушать ход событий и пытаться вступать там в непредусмотренные контакты.
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Reviewers' field: No. The aim of this work was to illustrate, by one difficult case patient, admitted in hospital, the diagnosis of B12 vitamin deficiency, intrigued with iron deficiency, because of multivitamin drugs, used as an individual treatment of patient, without a previous medical consult.
History: A 70 year old engineer, since 8 years vegetable — diet, was admitted to the county hospital in month august 20 —because of weakness, 10 kilo in last two months], dizziness, exertional dyspneea, ataxia and numbress of the hands, with lung disease in evolution.
Psychiatric symptoms such as memory disturbance, depression and cognitive decline have been also reported. After outcome from hospital, at home, neuroendocrine cancer day 2019 patient presented lipotimia status, confusion and was admitted in cardiology department. Hematologic analyser showed neutrophilia, lymphopenia and the microscopy exam on peripheral blood smears showed the dimorphic picture and pancytopenia.
At examination of bone morrow occurred increased erythropoiesis which was megaloblastic in character, giant band forms, large metamilocytes. Biopsy results from gastric mucosa showed lesions of chronic gastritis, non-atrophic.
Moderators: Prof. Norina Consuela Forna, Prof. Winter conditions in Romania.
Another para-clinical examinations [abdominal echografic, barium-rx exam], have been normally. Diagnosis: anemia by cobalamin deficiency and iron deficiency The patient followed therapeutic sample [with B12 vitamin, gamma, im. The blood neuroendocrine cancer day 2019 shows anisocytosis: normocytosis with ease macrocytosis. Efficiency of treatment in periodically will be monitored and by performing of metilmalonic acid test heparnied plasma and homocystein level EDTA plasma. Comment: In first time the neurogical manifestation occurred to patients in absence of blood picture in peripheral blood of typical megaloblastic anemia.
Не совсем, - ответил Ричард, поддразнивая. - Я по-прежнему люблю тебя, как мальчишка. но время от времени любовь отодвигается в сторону: тут болит, там болит. раньше со мной этого не бывало.
To the patient with vegetable diet anemia by B12 vitamin is accompanied of neurological syndrome with frequently iron deficiency, specialty to elder men.
This case illustrates many interesting points that are considered atypical of deficiency in B12 vitamin.
In first neuroendocrine cancer day 2019, the neurological manifestations occurred to this patient in the absence of anemia. When a patient with anemia by B12 vitamin deficiency has the neurological features of disease neuroendocrine cancer day 2019 the neuroendocrine cancer day 2019 hematologic abnormalities, the diagnosis is difficult. On such circumstance, the patient has received B12 vitamin and folic acid in an amount that is sufficient to convert the megaloblastic anemia type of erythropoiesis to the normoblastic type in peripheral blood and raise the erythrocyte count.
The anemia was normocytic and not associated with leucopenia, thrombocytemia in peripheral blood. The diagnosis of deficiency B12 vitamin was established by the response to specific therapy.
When and iron deficiency is severe the anemia is hypochromic and microcytic but in milder degrees of iron deficiency the anemia is normocytic.
A combined deficiency of iron B12 vitamin might result in a normocytic anemia that required both iron and vitamin Neuroendocrine cancer day 2019 in treatment . Impaired absorption of vitamin B12 occurs and in other conditions different of diet deficiencies associated with diarrhea or other evidence of the mal-absorption syndrome.
Such impairment has been demonstrated to patients with: - Blind intestinal loops, fistulae, strictures, and diverticula of the small bowel, - Gastrectomy, because absence of the gastric intrinsic factor, altered gastric secretion, gastric atrophy with degenerative lesions, mal-absorption syndrome, gastro duodenal disease and pancreatic, abnormal bacterial proliferations in bowel, infestation with parasites, failure pancreatic, liver, chronic hepatitis cirrhosis, - Disease of lymphoma group, myeloproliferative syndrome MSD by elevated consummations in neoplasia and hyperthyroid — but a study neuroendocrine cancer day 2019 the bone morrow usually enable one to establish the diagnosis .
In some patient particularly since the advent of folic acid and the widespread use of multivitamin preparations the aematological abnormalities are mild or absent when neurological manifestations are predominant.
The bone morrow is usually hyper-cellular. The characteristic feature is the occurrence of the megaloblastic type of erythropoiesis. If anemia is severe, promegaloblastic and basophilic megaloblasts are increased in number and mitotic divisions are numerous .
Andreea ILIESIU – MÆDICA – a Journal of Clinical Medicine
The polychromatophilic megaloblasts which are easiest cells to identify in this serious persist even after the anemia in the peripheral blood has been abolished by transfusion. Deficiency of vitamin B12 or folic acid also leads to the production of giant metamielocytes neuroendocrine cancer day 2019 multi-segmented macropolicites.
The abnormalities in the granulocytic series do not disappear as promptly as then megaloblasts after specific therapy and their present may be helpful in diagnosis. There are the conversion of the megaloblastic type of erythropoiesis to the normoblastic type within two day, a rise in reticolocytes during the first week, papilloma virus genitali femminili a return of the haemoglobin and red count to normal levels in succeeding weeks.
The recent years the picture has become more complex.