His complaints have begun 6 months before the admission. After four courses of BEP bleomycin, etoposide and cisplatinorchiectomy was performed and the patient was under surveillance in the oncology department.
Вот уж никогда не думал, что такое .
The degree of AFP elevation in patients with non-seminomatous germ cell tumours NSGCT establishes the prognosis and is used to assign an appropriate chemotherapy regimen. Keywords mature teratoma, lung metastases, alpha 1-fetoprotein, multidisciplinary treatment Rezumat Prezentăm cazul unui pacient în vârstă de 37 de ani, fără antecedente patologice semnificative, care s-a prezentat la camera de gardă cu testicular cancer with mets şi durere toracică apărute testicular cancer with mets cancer with mets un episod de hemoptizie, la examinarea testicular cancer with mets prezentând o formaţiune palpabilă la nivelul testiculului stâng.
Simptomatologia a început în urmă cu şase luni. După patru serii de BEP bleomycin, etoposide şi cisplatinse intervine chirurgical, practicându-se orhiectomie pe cale inghinală, ulterior pacientul rămânând în urmărire în Departamentul de oncologie medicală.
Creşterea AFP la pacienţii cu tumori germinale testiculare nonseminomatoase NSGCT are valoare prognostică şi este folosită pentru stabilirea unui tratament testicular cancer with mets potrivit. Cuvinte cheie teratom matur metastaze pulmonare AFP tratament multidisciplinar Case presentation We present the case of a year-old man, in clinical state of health until 6 months before the admission, when he began to notice a left-sided testicular swelling, but with no associated pain at the time.
The swelling progressed over the next few months, and was associated with dyspnea and chest pain. Also, he complained of weight loss about 10 kg in the past 6 months. He presented to the hospital in Augustafter one episode of haemoptysis, with severe dyspnea.
He smoked one pack of cigarettes a day for 12 years, and he used to drink alcoholic beverages on weekends. His family history revealed: the father with hypertension, and an uncle with type 2 diabetes. The other examinations were normal.
Laboratory tests at first testicular cancer with mets CBC showed a haemoglobin of PT prothrombin time was The imagistic exams performed in Septemberchest X-ray and CT scan of the chest Figure 1 and Figure 2showed multiple nodules with different sizes, and the probability of metastasis testicular cancer with mets propounded.
Figure 1. Chest X-ray: lung metastases Figure 2. Management: the therapeutic decision was planned by BEP bleomycin, etoposide and cisplatin as classic five-day protocol. After four cycles of BEP, the level of serum tumor markers reached the normal value, and we decided to perform a left orchiectomy, that had no intra- or postoperative complications.
The histopathologic examination showed mature teratoma inflitrative to the tunica albuginea and spermatic cord; the spermatic cord lymph node showed also mature teratoma, with pT3 pN2 stage stadialization.
Therefore, the decission was to start chemotherapy. In Marchthe check-up PET-CT showed once again activity in his lungs metastases, and also active metabolic lymph nodes latero-tracheal, hilar lymph nodeswith no other sites involvment.
At this moment, our testicular cancer with mets is at his fourth cycle of chemotherapy since we restarted. This distinction guides the clinician in both prognosis and treatment strategies.
Adăugați în lista de dorințe Instalați Traduceți descrierea în română folosind Google Traducere? Traduceți descrierea înapoi în engleză Statele Unite ale Americii Traduceți The staging of testis cancer refers to how far the cancer has spread.
Positron-emission thomography scan can also be used to highlight the hypermetabolic lymph node metastases. M1a — Non-regional nodal or pulmonary metastasis.
Tumoare germinală testiculară nonseminomatoasă cu prognostic rezervat
The patient is a unique case, showing a special significance and connection between AFP serum level, PET-CT hypermetabolic lymph nodes and the respose to chemotherapy. We are also looking testicular cancer with mets for new molecular targeted therapies with a good response in the treatment of germ cell tumors of patients with recurrence after salvage chemotherapy. Conflict of interests: The author declares no conflict of interests.
Testicular cancer survivor's advice for patients
Alpha-foetoprotein heterogeneity: cancer endometrial polyp is its value in managing testicular cancer with mets with germ cell tumours?.
Clin Oncol R Coll Radiol.
Non-seminomatous germ cell testicular tumor with poor prognosis
J Clin Oncol. De Vita et al. Cancers of the Genitourinary System. LWW Health Library.