Hepatocellular cancer metabolic syndrome

Sindromul metabolic și cancerul hepatocelular

The study was undertaken to evaluate the impact of type II diabetes on patients with hepatocellular carcinoma HCC.

  • NAFLD encompasses two distinct conditions with distinct histologic features and prognosis: 1 nonalcoholic fatty liver NAFLwhich includes steatosis only, and 2 nonalcoholic steatohepatitis NASH characterized by steatosis and inflammation with hepatocyte ballooning, with or without fibrosis, which can progress to liver fibrosis, cirrhosis, hepatocellular carcinoma HCC and liver transplantation 2.
  • Schistosomiasis pre sinusoidal

Material and methods. This is an observational study conducted in the Department of Oncology, Clinical Emergency County Hospital of Constanţa, for a period of four years, from to A total of patients with HCC were analyzed.

The patients were divided in two groups, with and without type II diabetes.

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In this study, there were included patients with hepatocellular carcinoma. Among all patients with HCC, 94 Of the patients with hepatocellular carcinoma, type II diabetes was found in 37 patients There is no difference between groups in relation to gender.

The average age in the group of HCC hpv wart color 70 years, compared to the group of hepatocellular cancer metabolic syndrome patients in which the mean hepatocellular cancer metabolic syndrome was of Hepatocellular carcinoma is a common cancer, with hepatocellular cancer metabolic syndrome incidence in our region, hepatitis C and B being shown to be the most frequent causative agent.

Type 2 diabetes was present in The average age at diagnosis of HCC within the group of diabetic patients was significantly lower. Mean survival was higher in non-diabetic patients and one-year mortality was significant higher in diabetic patients, concluding that diabetes may affect the long-term survival and can worsen the prognosis in these patients.

hepatocellular cancer metabolic syndrome

Studiul a fost făcut pentru a evalua impactul diabetului de tip II la pacienții diagnosticați cu carcinom hepatocelular HCC. Materiale și metode. Acesta este un studiu observațional desfățurat în Departamentul de Oncologie a Spitalului Județean de Urgență Constanța, cu hepatocellular cancer metabolic syndrome durată de patru ani, din până în Au fost analizați în studiu de pacienți cu HCC. Pacienții au fost împărțiți în două grupuri, cu și fără diabet de tip II.

Nu este nici o diferență între grupe în relație cu sexul pacienților.

Scientific Abstracts. National Symposium of Bariatric and Metabolic Surgery

Vârsta medie a grupului fără diabet a fost de 70 de ani, iar la cei cu diabet 65,38 de ani, cu o diferență semnificativă statistic. Carcinomul hepatocelular este un cancer frecvent, cu incidență crescută în regiunea noastră, cel mai întâlnit agent cauzal  fiind infecția cu virus hepatic B și C.

  • Sindromul metabolic și cancerul hepatocelular
  • Que es a cancer
  • Está en la página 1de 17 Buscar dentro del documento The Sixth National Symposium of Bariatric and Metabolic Surgery December 6th,Bucharest Carcinomul hepatocelular dezvoltat pe ficatul gras nonalcoolic.
  • Но он не подозревал, что наиболее важные элементы их коллективной информации хранятся в манно-дынях и передаются следующему поколению.

  • Да, - проговорил Орел.

Vârsta medie la diagnosticul HCC a fost semnificativ mai mică. Supraviețuirea medie a fost mai mare la pacienții non-diabetici și mortalitatea la un an a fost semnificativ mai mare la pacienții diabetici, relevând că diabetul hepatocellular cancer metabolic syndrome afecta supraviețuirea pe hepatocellular cancer metabolic syndrome lung și că reprezintă un factor de  prognostic negativ la acești pacienți.

Throughout the world, there are diagnosed each year approximatelynew cases hepatocellular cancer metabolic syndrome HCC. The most common and known risk factor are viral infection, hepatitis virus B or C, toxic factors - alcohol and aflatoxin, immune diseases like primary biliary cirrhosis, plus, in recent years, metabolic risk factors like diabetes and non-alcoholic hepatic steatosis 2,3.

hepatocellular cancer metabolic syndrome

Hepatocellular cancer metabolic syndrome possible explanation for the association of diabetes with hepatocellular carcinoma is that diabetes is often part of the metabolic syndrome characterized by clinical and biochemical changes that include alterations in glucose metabolism and insulin, causing hyperglycemia and hyperinsulinemia, dyslipidemia and hypertension. Metabolic disorders associated with metabolic syndrome can cause diabetes and furthermore contribute to the development of NAFLD non-alchoolic fatty liver disease and its most severe form, non-alcoholic steatohepatitis, so HCC can result from liver cirrhosis caused by NAFLD 4,5,6.


Type II diabetes has an increased incidence worldwide. Epidemiologically, the relationship between HCV infection and diabetes is known, diabetes being reported to increase the risk of hepatocellular carcinoma in patients with chronic hepatitic C and also contributes to the excess mortality in hepatocellular cancer metabolic syndrome patients 7,8.

Management of hepatocellular carcinoma is influenced by tumor status, liver function and by comorbidities, and diabetes is one of them 9, Material and methods This is an observational study conducted in the Department of Oncology, Clinical Emergency County Hospital of Constanţa, for a period of four years, from to One hundred and sixty-five patients diagnosed with hepatocellular carcinoma were included in this study.

Patients were divided in two groups regarding the presence or hepatocellular cancer metabolic syndrome of type II diabetes.

hepatocellular cancer metabolic syndrome

Demographic profile, clinical features, etiology, tumor size, hepatocellular cancer metabolic syndrome presence of portal vein thrombosis were compared between groups.

Data were evaluated using the statistical program SPSS Qualitative data included descriptive statistics, continuous variables are expressed as Hepatocellular cancer metabolic syndrome and Standard Deviation, and T test was used to compare the two groups.

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Results In this study, there were included patients with hepatocellular carcinoma. Demographic data are shown in Table 1. Mean age was Cirrhosis was present in 94 patients and absent in Among patients with hepatic cirrhosis, the higher percentage was class Child-Pugh B: 39 In table 2, there are shown the clinical features at the time of diagnosis of hepatocellular carcinoma with or without type II diabetes.

  1. Impactul diabetului de tip 2 asupra prognosticului pacienților cu carcinom hepatocelular
  2. В известном смысле, - ответил Арчи.

  3. Но можно было не сомневаться: легенда повествовала о давних событиях в истории октопауков.

  4. Tratament gripa a
  5. Наи рассказала о том, чем будут заниматься дети в школе с утра до дневного сна; Эпонина известила всех, что изжога и утренняя тошнота как будто бы ослабели; Ричард пожаловался на "биологических магов" - наших хозяев-октопауков.

Regarding liver cirrhosis, in the non-diabetic group it was present in a higher percentage compared with the group hepatocellular cancer metabolic syndrome diabetic patients, 78 cases Portal vein thrombosis is present in the group of non-diabetic patients in a percentage of Conclusions Hepatocellular hepatocellular cancer metabolic syndrome is a common cancer, with an increased incidence in our region, hepatitis C and B being shown to be the most frequent causative agent.

Type II diabetes was present in Cancer of the liver. Cancer: principles and practice of oncology.

hepatocellular cancer metabolic syndrome cancer pulmonar g2

Diabetes increases the risk of hepatocellular carcinoma in the United States: a population based case control study. Gut, ; Diabetes increases the risk of chronic liver disease and hepatocellular carcinoma.

Risk Factors for Hepatocellular Carcinoma

Gastroenterology, ; Cancer Lett, Further evidence for an association between non-insulindependent diabetes mellitus and chronic hepatitis C virus infection. Hepatology, ; 4 : Rathmann W, Giani G. Global prevalence of diabetes: estimates for the year and projections for Diabetes Care, ; 5 : Nasir Khokhar.

Association of chronic hepatitis C virus infection and diabetes mellitus.

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Pak J Med Res, ; 41 4 : Excess risk of primary liver cancer in patients with diabetes mellitus. J Natl Cancer Inst, ; 20 : Impact of diabetes mellitus on the prognosis of patients with hepatocellular carcinoma.